Coding

Part:BBa_K2608008

Designed by: Guijie Ren   Group: iGEM18_JNFLS   (2018-10-07)


truncated and optimized HCV core protein (173 aa)

(519bp) truncated and optimized HCV core protein (173 aa)

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    INCOMPATIBLE WITH RFC[12]
    Illegal NotI site found at 176
  • 21
    INCOMPATIBLE WITH RFC[21]
    Illegal BglII site found at 393
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


HCV is a single strand RNA virus with coat. Core antigen is the main protein of nucleocapsid. It is an important part of the virus particle. Core protein can controll the virus itself, as well as the interactions of virus and host cells. After signal peptide was inserted to the 5’-UTR of HCV C gene, the expressed fusion protein can be secreted to the outside of the cell, with the ability of self-assembly into virus particle. Ii is a very good tool for HCV research.

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